Neonatal Sepsis

Neonatal sepsis is an invasive infection that typically occurs during the neonatal era and is caused by bacteria. Reduced spontaneous activity, less vigorous sucking, apnea, bradycardia, temperature instability, respiratory distress, vomiting, diarrhoea, abdominal distention, jitteriness, convulsions, and jaundice are a few of the numerous, nonspecific signs. Clinical findings are used to make the diagnosis. Ampicillin and either gentamicin or cefotaxime are used as the first line of treatment before being quickly narrowed down to medications that are specific to the organism.

Neonatal sepsis occurs in 0.5 to 8.0/1000 births. The highest rates occur in

  • infants with low Apgar scores at birth, indicating decreased function,
  • infants with prenatal risk factors in their mothers (eg, low socioeconomic status, premature rupture of membranes)
  • Minorities
  • Males

 

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